United States securities and exchange commission logo

                     February 10, 2023

       Frederic Guerard, Pharm.D.
       President and Chief Executive Officer
       Graybug Vision, Inc.
       203 Redwood Shores Parkway, Suite 620
       Redwood City, CA 94065

                                                        Re: Graybug Vision,
                                                            Preliminary Proxy
Statement on Schedule 14A
                                                            Filed December 14,
                                                            File No. 001-39538

       Dear Frederic Guerard:

              We have completed our review of your filing. We remind you that
the company and its
       management are responsible for the accuracy and adequacy of their
disclosures, notwithstanding
       any review, comments, action or absence of action by the staff.


                     Division of Corporation Finance

                     Office of Life Sciences
       cc:                                              Julia Forbess, Esq.